Pain Patterns of the Temporomandibular Joint Dysfunction and Implications of Stress-Related Behaviors: A Pilot Study / Patrones de Dolor de la Disfunción de la Articulación Temporomandibular e Implicaciones de los Comportamientos Relacionados con el Estrés: Un Estudio Piloto

SUMMARY: Temporomandibular joint dysfunction interferes with the quality of life and activities of daily living among patients. The symptoms of temporomandibular dysfunction, including pain and clicking and popping sounds, are worsened during stressful events, and patients report increased pain around the temporomandibular joint. Stress-related behaviors, such as teeth clenching and teeth grinding, are commonly reported as increasing during stress. The prevalence of temporomandibular dysfunction and stress-related behaviors is reported differently in the literature. Stress in higher education is common. The purpose of this pilot study was to investigate the prevalence of temporomandibular joint dysfunction and stress-related behaviors among staff members at a local University. The study also sought to explore pain patterns described by people experiencing temporomandibular joint dysfunction and the relationship between stress-related behaviors and pain symptoms experienced. Further, the impact of stress on symptoms experienced by people with temporomandibular dysfunction was investigated in this pilot study.

La disfunción de la articulación temporomandibular interfiere con la calidad de vida y las actividades de la vida diaria entre los pacientes. Los síntomas de la disfunción temporomandibular, incluidos el dolor y los chasquidos, empeoran durante los eventos estresantes, y los pacientes informan un aumento del dolor alrededor de la articulación temporomandibular. Los comportamientos relacionados con el estrés, como apretar y rechinar los dientes, suelen aumentar durante el estrés. La prevalencia de la disfunción temporomandibular y los comportamientos relacionados con el estrés se informa de manera diferente en la literatura. El estrés en la educación superior es común. El propósito de este estudio piloto fue investigar la prevalencia de la disfunción de la articulación temporomandibular y los comportamientos relacionados con el estrés entre los miembros del personal de una universidad local. El objetivo del estudio además fue explorar los patrones de dolor descritos por personas que experimentan disfunción de la articulación temporomandibular y la relación entre los comportamientos relacionados con el estrés y los síntomas de dolor experimentados. Además, en este estudio piloto se investigó el impacto del estrés en los síntomas que experimentan las personas con disfunción temporomandibular.

Estudio Piloto Comparativo entre la Identificación Dactiloscópica y Poroscópica con Fines de Identificación Humana en el Perú / Comparative Pilot Study Between Dactyloscopy Identification and Poroscopy for Human Identification Purposes in Peru

La dactiloscopía o papiloscopía corresponde al estudio científico de las impresiones digitales, palmares y plantares, que tiene por finalidad la identificación infalible o indubitada del individuo. Existen tres niveles para identificar con mayor certeza nivel 1 (tipo o patrón dactilar), el nivel 2 (minucias o puntos característicos) y el nivel 3 (poroscopia y crestoscopia). Por ello, es necesario analizar las características de las impresiones dactilares directas y las huellas dactilares directas con la finalidad de verificar la presencia de puntos y poros característicos para mejorar el proceso de identificación humana. Se analizaron 80 muestras (54 mujeres y 26 hom- bres). A partir de ellos, se capturaron 800 impresiones y 800 huellas dactilares directas con tampón dactilar y polvo black. En huellas con tampón se identificaron 71.25 % y 1.25 % con 14 y 6 Puntos Característicos respectivamente y en grupos de poros el 84 % y 35 % para un grupo de 1 y grupos de 7 y 8 poros respectivamente. Con polvo black solo se identificaron Puntos Característico y no Poros. La cantidad de poros en hombres fue mayor igual a 10 (LR= 2.08) y en mujeres menor igual a 6 (LR= 1.93). Los grupos de poros fueron para hombres menores o iguales a 12 poros (LR= 1.04) y mayores o iguales a grupos de 13 poros (LR=1.28) para mujeres. Se consiguieron identificar grupos de poros con tampón dactilar pero no con polvos químicos lo que podría emplearse para implementar un protocolo para el uso del nivel 3 de identificación.

SUMMARY: Dactyloscopy or papiloscopy corresponds to the scientific study of digital, palmar and plantar impressions, whose purpose is the infallible or indubitable identification of a subject. There are three levels to identify with greater certainty level 1 (type or fingerprint pattern), level 2 (minutiae or characteristic points) and level 3 (poroscopy and crestoscopy). Therefore, it is necessary to analyze the characteristics of direct fingerprints and direct fingerprints in order to verify the presence of characteristic points and pores to improve the human identification process. 80 samples (54 women and 26 men) were analyzed. Of these, 800 impressions and 800 direct fingerprints with fingerprint buffer and black powder were captured. In footprints with buffer, 71.25 % and 1.25 % were identified with 14 and 6 Characteristic Points respectively and in groups of pores 84 % and 35 % for a group of 1 and groups of 7 and 8 pores respectively. With black powder, only Characteristic Points and no Pores were identified. The number of pores in men was greater than 10 (LR= 2.08) and in women less than 6 (LR= 1.93). The groups of pores were less than or equal to 12 pores (LR= 1.04) for men and greater than or equal to groups of 13 pores (LR=1.28) for women. It was possible to identify groups of pores with a fingerprint buffer but not with chemical powders, which could be used to implement a protocol for the use of level 3 identification.

Escala de estratégias de resolução de conflitos familiares: adaptação e evidências psicométricas / Family conflict resolution strategies scale: adaptation and psychometric evidence / Escala de estrategias de resolución de conflictos familiares: adaptación y evidencias psicométricas

Este estudo teve o objetivo de adaptar o Conflict Resolution Styles Inventory (CRSI) para o contexto brasileiro e investigar se este apresenta evidências de adequabilidade psicométrica. No Estudo 1 foi desenvolvida a versão brasileira e, posteriormente, foram analisadas evidências de validade de conteúdo por meio da análise de juízes (N = 4 avaliadores especialistas) e adequação semântica em um estudo piloto com adolescentes (N = 15). No Estudo 2, verificamos as propriedades psicométricas do CRSI em uma amostra de adolescentes (N = 276), reunindo evidências de validade de estrutura interna e precisão. Finalmente, no Estudo 3, foram investigadas evidências adicionais de estrutura interna e precisão do CRSI em uma nova amostra (N = 224). Os resultados demonstraram que o CRSI reúne evidências de validade com base no conteúdo, na estrutura interna e de precisão, podendo ser usado para avaliar as estratégias de resolução de conflitos que adolescentes brasileiros utilizam nas discordâncias com seus pais, possibilitando seu uso em pesquisas sobre esse tema.(AU)

This study adapted the Conflict Resolution Styles Inventory (CRSI) for the Brazilian context and assessed its psychometric adequacy. In Study 1, the Brazilian version was developed and content validity was analyzed by experts (N = 4) with semantic adequacy assessed in a pilot study with adolescents (N = 15). In Study 2, psychometric properties were examined in a sample of adolescents (N = 276), providing evidence of internal validity and reliability. Study 3 further investigated evidence of internal validity and reliability in a new sample (N = 224). Results indicated that the CRSI exhibits content validity, internal validity, and reliability, making it suitable for assessing conflict resolution strategies employed by Brazilian adolescents in disagreements with their parents, enabling its use in related research.(AU)

Este estudio tuvo como objetivo adaptar el Conflict Resolution Styles Inventory (CRSI) al contexto brasileño y verificar si presenta evidencias de adecuación psicométrica. En el Estudio 1, se desarrolló la versión brasileña y, posteriormente, se analizaron las evidencias de validez de contenido a través del análisis de jueces (N = 4 evaluadores expertos) y de adecuación semántica en un estudio piloto con adolescentes (N = 15). En el Estudio 2, verificamos las propiedades psicométricas del CRSI en una muestra de adolescentes (N = 276), recogiendo evidencias de validez interna y precisión. Finalmente, en el Estudio 3, se investigó evidencias adicionales de la validez interna y precisión del CRSI en una nueva muestra (N = 224). Los resultados mostraron que el CRSI reúne evidencias de validez de contenido, validez interna y precisión, y puede ser utilizado para evaluar las estrategias de resolución de conflictos utilizadas por adolescentes brasileños en desacuerdos con sus padres, lo que permite su uso en investigaciones sobre este tema.(AU)

Perfis de jogo de crianças: adaptação do Children's Play Therapy Instrument (CPTI) / Play profiles of children: adaptation of the Children's Play Therapy Instrument (CPTI) / Perfiles de juego de niños: adaptación del Children's Play Therapy Instrument (CPTI)

O brincar e a vida infantil estão inevitavelmente entrelaçados, havendo inúmeras evidências da ação terapêutica do brinquedo para o desenvolvimento infantil e, consequentemente, para o desenrolar da Psicoterapia Psicodinâmica (PP). Para acessar o brincar de crianças de maneira objetiva durante o percurso da PP, foi desenvolvido o Children's Play Therapy Instrument (CPTI). O objetivo desse estudo foi adaptar para o português o CPTI, assim como realizar um estudo piloto para identificar evidências de validade do instrumento, através da análise de perfis de jogo de psicoterapias de três crianças, uma menina e dois meninos, com oito, sete e oito anos, diagnosticados com transtorno de adaptação, transtorno disruptivo da desregulação do humor e transtorno do espectro autista, nível 1, respectivamente. A versão em português do CPTI apresentou boa equivalência com a original e a fidedignidade interavaliadores foi alta, além de serem encontradas evidências preliminares de validade. O instrumento foi capaz de diferenciar os perfis de jogo de cada criança, descrevendo atividades de jogo condizentes com as psicopatologias analisadas. As possibilidades e limitações de utilização do instrumento foram discutidas. (AU)

Play and childhood are inevitably intertwined, with numerous indications of the therapeutic effects of play on child development and, consequently, on the progress of Psychodynamic Psychotherapy (PP). To access children's play during the course of PP, the Children's Play Therapy Instrument (CPTI) was developed. The aim of this study was to adapt the CPTI to Portuguese and to conduct a pilot study to identify validity evidence for the instrument through the analysis of play profiles of psychotherapies involving three children: one girl and two boys, aged eight, seven, and eight, respectively. They were diagnosed with adjustment disorder, disruptive mood dysregulation disorder, and autism spectrum disorder level 1. The Portuguese version of the CPTI showed good equivalence to the original, inter-rater reliability was high, and preliminary evidence of validity was found. The instrument was able to differentiate each child's play profiles, describing play activities consistent with the psychopathologies analyzed. The instrument's possibilities and limitations were discussed. (AU)

El juego y la vida de los niños están inevitablemente entrelazados, con numerosas evidencias de la acción terapéutica del juguete para el desarrollo infantil y, en consecuencia, para el desarrollo de la Psicoterapia Psicodinámica (PP). Para acceder de forma objetiva al juego infantil durante el transcurso de la PP, se desarrolló el Instrumento de Terapia de Juego Infantil (CPTI). El objetivo de este estudio fue adaptar el CPTI al portugués, así como realizar un estudio piloto para identificar evidencias de validez del instrumento, a través del análisis de perfiles de juego de tres psicoterapias con tres niños, se incluye una niña y dos niños de ocho, siete y ocho años, diagnosticados con trastorno de adaptación, trastorno de desregulación disruptiva del estado de ánimo y trastorno del espectro autista, nivel 1, respectivamente. El CPTI mostró una buena equivalencia con el original y la confiabilidad entre evaluadores fue alta. El instrumento logró diferenciar los perfiles de juego de cada niño, describiendo actividades de juego consistentes con las psicopatologías analizadas. Se discutieron las posibilidades y limitaciones del uso del instrumento. (AU)

Tiempo empleado para estimar edad dental en niños peruanos comparando el método de Demirjian y el cuadro integral del enfoque de Demirjian: un estudio piloto / Time spent to estimate dental age in peruvian children comparing the demirjian method and the comprehensive chart based on demirjian method: a pilot study

El objetivo de este estudio fue comparar el tiempo empleado al estimar la edad dental (ED) entre el método propuesto por Demirjian et al. y el cuadro integral del enfoque de Demirjian (DAEcc) utilizando radiografías panorámicas digitales de individuos peruanos de 5 a 13 años residentes en Lima. Se realizó un estudio no experimental, comparativo, transversal y retrospectivo. Se utilizaron 100 radiografías panorámicas digitales que presentaban siete dientes permanentes mandibulares izquierdos. Una odontóloga forense capacitada y calibrada determinó el tiempo utilizado en evaluar la maduración dental y la estimación de ED con dos métodos (Demirjian y DAEcc). La unidad de medida utilizada fue los minutos (min.). No hubo diferencias en el tiempo de evaluación del estadio de maduración dental entre ambos métodos (p<0,05). El tiempo para estimar ED fue estadísticamente inferior con DAEcc (2,09 min) que con Demirjian (4,19 min). La diferencia del tiempo total de evaluación resultó estadísticamente significativa entre ambos métodos (Δ2,1 min.; 2,05-2,11; p=0,000). La aplicación del DAEcc redujo en 50 % el tiempo empleado en estimar ED en comparación con los cuadros propuestos por Demirjian. Aunque la odontología forense se centra en el estudio de la eficacia de estimación de la edad, es necesario abordar también su uso práctico.

SUMMARY: The objective of this study was to compare the time used to estimate dental age (DA) between the method proposed by Demirjian et al., and the comprehensive chart for dental age estimation (DAEcc) using digital panoramic radiographs of Peruvian individuals aged 5 to 13 years residing in Lima. A non- experimental, comparative, cross-sectional and retrospective study was carried out. 100 digital panoramic radiographs showing seven mandibular left permanent teeth were used. A trained and calibrated forensic odontologist determined the time used to assess tooth maturation and DA estimation with two methods (Demirjian and DAEcc). The unit of measurement used was minutes (min.). There were no differences in the evaluation time of the dental maturation stage between both methods (p<0.05). The time spent to estimate DA was statistically less with DAEcc (2.09 min) than with Demirjian (4.19 min). The difference in total evaluation time was statistically significant between both methods (Δ2.1 min; 2.05-2.11; p=0.000).The application of DAEcc reduced by 50 % the time spent estimating DA compared to the method proposed by Demirjian. Although forensic odontology focuses on the study of the effectiveness of age estimation, its practical use needs to be addressed as well.

Anamnesis ambiental como parte de la consulta pediátrica: estudio piloto / Environmental history-taking as part of pediatric consultations: a pilot study

Introducción. La salud ambiental infantil es la rama de la pediatría que estudia la influencia del medioambiente en la salud y la enfermedad de los niños. Las exposiciones ambientales globales representan una seria amenaza para la salud, lo que justifica una mayor investigación y acción. Objetivo. Evaluar la salud ambiental de una muestra de niños que viven en áreas urbanas y rurales de la ciudad de Uruguaiana, Brasil. Población y métodos. Se incluyeron padres/tutores (n = 714) de niños atendidos en el Policlínico Infantil de la Ciudad de Uruguaiana de enero a octubre de 2021, que respondieron la anamnesis ambiental en pediatría (Sociedad Brasileña de Pediatría). Los datos obtenidos se analizaron según la residencia en zona urbana o rural, o el ingreso familiar. Resultados. Al comparar los habitantes de la zona urbana (n = 660) con los de la zona rural (n = 54), verificamos que entre los de la zona rural fue significativamente mayor la actividad con productos químicos (15 % vs. 32,7 %; p = 0,004), vivir cerca de plantación (7,5 % vs. 74,5 %; p <0,001) o con fuente de contaminación (4,8 % vs. 32,7 %; p <0,001), tener perro (62 % vs. 87,3 %; p <0,001), usar plaguicidas (0,6 % vs. 32,7 %; p <0,001) y exposición a contaminación química (2,6 % vs. 18,2 %; p <0,001). En el área urbana predominó la exposición al tránsito de vehículos cerca de la vivienda (85 % vs. 48,1 %; p <0,001), renta media inferior a 3 salarios mínimos (90 %) y baja escolaridad. Conclusión. Realizar la anamnesis ambiental es fundamental para la detección de amenazas ambientales presentes en los lugares donde los niños y adolescentes viven, aprenden, juegan y estudian.

Introduction. Children's environmental health studies the influence of the environment on health and disease in children. Global environmental exposures pose a serious threat to health, warranting further research and action. Objective. To assess the environmental health of a sample of children living in urban and rural areas in Uruguaiana, Brazil. Population and methods. We included parents/legal guardians (n = 714) of children seen at Policlinica Infantil de Uruguaiana between January and October 2021, who completed the environmental history- taking in pediatrics (Brazilian Society of Pediatrics). Collected data were analyzed based on place of residence (urban or rural) or household income. Results. The comparison between inhabitants of the urban area (n = 660) and the rural area (n = 54) established that, among those living in the rural area, activity with chemical substances (15% versus 32.7%; p = 0.004), living near a plantation (7.5% versus 74.5%; p < 0.001) or near a source of contamination (4.8% versus 32.7%; p < 0.001), having a dog (62% versus 87.3%; p < 0.001), using pesticides (0.6% versus 32.7%; p < 0.001), and exposure to chemical contamination (2.6% versus 18.2%; p < 0.001) were significantly higher. In the urban area, exposure to vehicle traffic near the house (85% versus 48.1%; p < 0.001), an average income below 3 minimum wages (90%), and a low level of education predominated. Conclusion. Environmental history-taking is critical for the detection of environmental threats present in the areas where children and adolescents live, learn, play, and study

[Errata] Estudo piloto sobre diâmetro do canal lombar e distância percorrida em pacientes com estenose espinhal lombar: um modelo de predição multivariado / [Erratum] Pilot study on lumbar canal diameter and walking distance in patients with lumbar spinal stenosis: a multivariate prediction model

INTRODUCTION: Neurogenic claudication (NC) is the classic clinical presentation of patients with Lumbar Spinal Stenosis (LSS). These patients may or may not present with symptoms of leg pain and difficulty walking. These symptoms are exacerbated while walking and standing and are eased by sitting or bending forward. METHOD: Patients with LSS, having a lumbar canal diameter of ≤12mm, were recruited from a recognized Tertiary care hospital. Each subject's demographic characteristics and anthropometrics were noted, and the testing procedure was explained. The canal diameter was documented with the help of an MRI report. A self-paced walking test was used to assess the walking distance. STATISTICAL ANALYSIS: Depending on the normality of the data, the Pearson correlation coefficient (r) was used to find the correlation between canal diameter at different lumbar levels and walking distance in patients with LSS. RESULT: Pearson correlation coefficient (r) determined a fair positive correlation (r = 0.29) between lumbar canal diameter and walking distance. Stepwise multiple regression analysis was done, and a prediction equation was found for different levels of canal stenosis. CONCLUSION: Findings of our present study suggest a fair positive correlation between walking distance and canal diameter at L5-S1. This study may also be useful in predicting the approximate canal diameter by estimating the walking distance of the patient with symptoms of LSS and vice-versa.

INTRODUÇÃO: A claudicação neurogênica (CN) é a apresentação clínica clássica de pacientes com Estenose Espinhal Lombar (EEL). Esses pacientes podem ou não apresentar sintomas de dor nas pernas e dificuldade para caminhar. Esses sintomas são exacerbados ao caminhar e ficar em pé e são aliviados ao sentar ou inclinar-se para a frente. MÉTODO: Pacientes com EEL, com diâmetro do canal lombar ≤12mm, foram recrutados em um hospital terciário reconhecido. As características demográficas e antropométricas de cada sujeito foram anotadas e o procedimento do teste foi explicado. O diâmetro do canal foi documentado com a ajuda de um relatório de ressonância magnética. Um teste de caminhada individualizado foi usado para avaliar a distância percorrida. ANÁLISE ESTATÍSTICA: Dependendo da normalidade dos dados, o coeficiente de correlação de Pearson (r) foi usado para encontrar a correlação entre o diâmetro do canal em diferentes níveis lombares e a distância percorrida em pacientes com EEL. RESULTADO: O coeficiente de correlação de Pearson (r) determinou uma correlação positiva razoável (r = 0,29) entre o diâmetro do canal lombar e a distância percorrida. Análise de regressão múltipla stepwise foi feita, e uma equação de predição foi encontrada para diferentes níveis de estenose do canal. CONCLUSÃO: Os achados de nosso estudo sugerem uma correlação positiva razoável entre a distância percorrida e o diâmetro do canal em L5-S1. Este estudo também pode ser útil para prever o diâmetro aproximado do canal, estimando a distância percorrida pelo paciente com sintomas de EEL e vice-versa.

Toll-like receptor 9 polymorphisms in brazilian patients with systemic lupus erythematosus: a pilot study / Polimorfismos do receptor toll-like 9 em pacientes brasileiros com lúpus eritematoso sistêmico: um estudo piloto

Abstract Toll-like receptor 9 (TLR9) is an important component of the innate immune system and have been associated with several autoimmune diseases, such as Systemic Lupus Erythematosus (SLE). The aim of this study was to investigate polymorphisms in TLR9 gene in a Brazilian SLE patients group and their association with clinical manifestation, particularly Jaccoud's arthropathy (JA). We analyzed DNA samples from 204 SLE patients, having a subgroup of them presenting JA (n=24). A control group (n=133) from the same city was also included. TLR9 single nucleotide polymorphisms (SNPs) (−1237 C>T and +2848 G>A) were identified by sequencing analysis. The TLR9 gene genotype frequency was similar both in SLE patients and the control group. In the whole SLE population, an association between the homozygosis of allele C at position −1237 with psychosis and anemia (p < 0.01) was found. Likewise, the homozygosis of allele G at position +2848 was associated with a discoid rash (p < 0.05). There was no association between JA and TLR9 polymorphisms. These data show that TLR9 polymorphisms do not seem to be a predisposing factor for SLE in the Brazilian population, and that SNPs are not associated with JA.

Resumo O receptor Toll-like 9 (TLR9) é um componente importante do sistema imunológico inato e tem sido associado a várias doenças autoimunes, como o Lúpus Eritematoso Sistêmico (LES). O objetivo deste estudo foi investigar polimorfismos no gene TLR9 em um grupo de pacientes brasileiros com LES e sua associação com a manifestação clínica, particularmente a artropatia de Jaccoud (JA). Foram analisadas amostras de DNA de 204 pacientes com LES, e um subgrupo com JA (n=24). Um grupo de controle (n=133) da mesma cidade também foi incluído. Os polimorfismos de nucleotídeos únicos TLR9 (SNPs) (−1237 C>T e +2848 G>A) foram identificados pela análise de sequenciamento. A frequência do genótipo genético TLR9 foi semelhante tanto em pacientes com LES quanto no grupo controle. Em toda a população de LES, foi encontrada associação entre a homozigose do alelo C na posição −1237 com psicose e anemia (p < 0,01). Da mesma forma, a homozigose do alelo G na posição +2848 foi associada a uma erupção cutânea discoide (p < 0,05). Não houve associação entre polimorfismos JA e TLR9. Esses dados mostram que os polimorfismos TLR9 não parecem ser um fator predisponível para o LES na população brasileira, e que os SNPs não estão associados ao JA.

Evaluation of an investigational hearing screening device (HeLe) to demonstrate acoustic brainstem response among normal-hearing adults

Objective@#This pilot human trial demonstrates the ability of the investigational newborn hearing screening device to provide acoustic stimulation to produce evoked potentials, as well as its ability to capture and acquire auditory evoked potentials, especially the auditory brainstem response (ABR) wave V. This pilot study also demonstrates the ease of recognizing and identifying ABR waves in the graphical presentation of the evoked potentials over time. @*Methods@#Fourteen normal-hearing adults or a total of twenty-eight (28) normal-hearing adult ears underwent auditory brainstem response testing using the investigational hearing screening device. A commercially available auditory brainstem response detection device was used to confirm that the acquired ABR waves of the investigational device are normal. The ABR waves displayed by the investigation device were also reviewed by the clinical audiologists to determine their recognizability and identifiability. @*Results@#The pilot trial demonstrates the ability of the investigational newborn hearing screening device in providing acoustic stimulation to produce evoked potentials, and in acquiring and capturing ABR waves, specifically the wave V, among normal-hearing adult ears. The clinical audiologists recognized and identified the ABR wave V among the evoked potentials at 40dB, 60dB, and 80dB acoustic stimulation. About eighty-nine percent (89.2%) of all ears tested had identifiable and recognizable wave V upon acoustic stimulation at 40dB. @*Conclusion@#The investigational hearing screening device: (1) can provide acoustic stimulation to produce evoked potentials, (2) can accurately capture and acquire these evoked potentials, (3) can present these evoked potentials in a voltage per time graphical display which an audiologist and trained HCP can easily read and interpret (diagnostic ABR), and (4) can present wave V auditory brainstem potentials that can be easily identified by an audiologist and trained HCP (screening ABR).

A pilot study on the effects of early use of valproate sodium on neuroinflammation after traumatic brain injury / 中国当代儿科杂志

OBJECTIVES@#To study the effect of early use of sodium valproate on neuroinflammation after traumatic brain injury (TBI).@*METHODS@#A total of 45 children who visited in Xuzhou Children's Hospital Affiliated to Xuzhou Medical University from August 2021 to August 2022 were enrolled in this prospective study, among whom 15 healthy children served as the healthy control group, and 30 children with TBI were divided into a sodium valproate treatment group and a conventional treatment group using a random number table (n=15 each). The children in the sodium valproate treatment group were given sodium valproate in addition to conventional treatment, and those in the conventional group were given an equal volume of 5% glucose solution in addition to conventional treatment. The serum concentrations of nucleotide-binding oligomerization domain-like receptor protein 3(NLRP3), high-mobility group box 1 (HMGB1), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β) were measured in the healthy control group on the day of physical examination and in the children with TBI on days 1, 3, and 5 after admission. Glasgow Outcome Scale-Extended (GOS-E) score was evaluated for the children with TBI 2 months after discharge.@*RESULTS@#Compared with the healthy control group, the children with TBI had significantly higher serum concentrations of NLRP3, HMGB1, TNF-α, and IL-1β on day 1 after admission (P<0.017). The concentration of NLRP3 on day 5 after admission was significantly higher than that on days 1 and 3 after admission in the children with TBI (P<0.017). On days 3 and 5 after admission, the sodium valproate treatment group had a significantly lower concentration of NLRP3 than the conventional treatment group (P<0.05). For the conventional treatment group, there was no significant difference in the concentration of HMGB1 on days 1, 3, and 5 after admission (P>0.017), while for the sodium valproate treatment group, the concentration of HMGB1 on day 5 after admission was significantly lower than that on days 1 and 3 after admission (P<0.017). On day 5 after admission, the sodium valproate treatment group had a significantly lower concentration of HMGB1 than the conventional treatment group (P<0.05). For the children with TBI, the concentration of TNF-α on day 1 after admission was significantly lower than that on days 3 and 5 after admission (P<0.017). On days 3 and 5 after admission, the sodium valproate treatment group had a significantly lower concentration of TNF-α than the conventional treatment group (P<0.05). The concentration of IL-1β on day 3 after admission was significantly lower than that on days 1 and 5 after admission (P<0.017) in the children with TBI. On days 3 and 5 after admission, the sodium valproate treatment group had a significantly lower concentration of IL-1β than the conventional treatment group (P<0.05). The GOS-E score was significantly higher in the sodium valproate treatment group than that in the conventional treatment group 2 months after discharge (P<0.05).@*CONCLUSIONS@#Early use of sodium valproate can reduce the release of neuroinflammatory factors and improve the prognosis of children with TBI.

Translation and Cross-Cultural Adaptation of the "Child Drawing: Hospital" (CD:H) Scale for Paediatric Dentistry in Brazil

Abstract Objective: To translate and perform the cross-cultural adaption of the CD:H scale for use in Paediatric Dentistry in Brazilian Portuguese language. Material and Methods: The translation and cross-cultural adaptation of the CD: H was carried out in four stages: 1) translation of the instrument; 2) reverse translation (back translation); 3) cross-cultural adaptation, and 4) face validation. Face validation consisted of the evaluation of 30 subjects from the target population. A pilot study was conducted with 15 children aged 5-10 years treated at a university dental clinic and their drawings were analysed by two dentists. Data were analysed using Stata 12.0. Results: In the face validation, most items were understood; however, some words were changed, and terms were included to identify the dental environment. Good reproducibility was obtained: inter-examiner reliability was 0.9647 and intra-examiner reliability was 0.9619 for examiner A and 0.8260 for examiner B. Conclusion: The Brazilian version of the CD:H scale is a useful tool for dentists, helping identify children's emotions and being enjoyable for them.

A 12-month Follow-Up Study of Pulp Oxygen Saturation in Deciduous Molars After Selective and Nonselective Carious-Tissue Removal: A Randomized Pilot Trial

ABSTRACT Objective: To compare the pulp vitality of deciduous molars before and after selective caries removal (SCR) or nonselective caries removal to hard dentin (NSCR) over one year, using oxygen saturation percentage (%SaO2). Material and Methods: Deciduous molars with deep occlusal/proximal-occlusal caries lesions were randomized to SCR (n=22) or NSCR groups (n=22). After the caries removal, the teeth were protected with calcium hydroxide cement and restored with composite resin (Filtek Z250). The pulp condition diagnosis was evaluated at baseline, immediately after caries removal, and follow-up (7 days, 1-, 6- and 12-months) by %SaO2. Pulp exposure and pulp necrosis were primary outcomes, and %SaO2 was secondary. Results: Intraoperative pulp exposure occurred in four teeth of the NSCR group (18.2%) and one tooth of the SCR group (4.5%) (p>0.05). Two cases of pulp necrosis occurred in the NSCR group (10%). No difference in %SaO2 pulp was observed in the inter-and intragroup comparison over time (p>0.05). Conclusion: Advantageously, the %SaO2 minimizes preoperatory pulp vitality diagnosis subjectivity before SCR/ NSCR treatments. Furthermore, the pilot study results suggest the pulp response of deciduous molars, when evaluated by clinical, radiographic, and pulp %SaO2 seems not to differ between teeth treated with SCR or NSCR.

Trastorno por Déficit de Atención e Hiperactividad (TDHA) y trastornos del estado del ánimo en estudiantes de medicina humana peruanos: una prueba piloto a nivel nacional / Attention Deficit Hyperactivity Disorder (ADHD) and mood disorders in Peruvian human medicine students: a nationwide pilot test

Introducción: el Trastorno por Déficit de Atención con Hiperactividad, también conocido por sus siglas TDAH, es considerado como un trastorno del neurodesarrollo. Diversos estudios reportan que la persistencia de los síntomas durante la adultez se da en el 50-70% de niños con TDAH. Respecto del área académica, la literatura menciona que esta patología en la población universitaria oscila entre un 10 a 25% de estudiantes, en particular los de Medicina Humana. Materiales y métodos: estudio piloto con diseño Cross-sectional, para explorar las variables mencionadas en los estudiantes de todo el territorio peruano se agruparon los departamentos en cinco macro regiones, se utilizaron los cuestionarios ASRS V1.1 y DASS-21. Resultados: se contó muestra total de 250 participantes para la prueba piloto (50 por cada macro región), respecto del TDAH, 33,6% presentó resultados sugestivos. La prevalencia de trastornos del estado anímico fue del 81,6%, dentro de ellos la ansiedad fue más prevalente (70,4%), seguido por la depresión (62,8%) y el estrés (57,6%). Se encontró asociación entre el TDAH y los siguientes: trastorno anímico (PR=1,3 IC(95%) ), depresión (PR=1,51 IC(95%) ), ansiedad (PR=1,47 IC(95%) ) y estrés (PR=1,87 IC(95%) ). Conclusiones: el presente estudio piloto nos ha permitido probar satisfactoriamente el desempeño del instrumento y la técnica propuesta por el diseño metodológico en el estudio primario, confirmado con la obtención de cifras estimadas coherentes con lo descrito por la literatura, y confirmando la asociación entre las variables de interés.

Introduction: Attention Deficit Hyperactivity Disorder, also known by its acronym ADHD, is considered a neurodevelopmental disorder. Several studies report that the persistence of symptoms during adulthood occurs in 50-70% of children with ADHD. Regarding the academic area, the literature mentions that this pathology in the university population ranges from 10 to 25% of students, in particular those of human medicine. Materials and methods: pilot study with Cross-sectional design, to explore the variables mentioned in students from all over the Peruvian territory, the departments were grouped into 5 macro regions, the ASRS V1.1 and DASS-21 questionnaires were used. Results: a total sample of 250 participants was counted for the pilot test (50 for each macro region), regarding ADHD, 33.6% presented suggestive results. The prevalence of mood disorders was 81.6%, among them, anxiety was more prevalent (70.4%), followed by depression (62.8%) and stress (57.6%). An association was found between ADHD and the following: Mood disorder (PR=1.3 CI (95%) ). Depression (PR=1.51 CI (95%) ). Anxiety (PR=1.47 CI (95%) ). and Stress (PR=1.87 CI (95%) ). Conclusions: the present pilot study has allowed us to satisfactorily test the performance of the instrument and the technique proposed by the methodological design in the primary study, confirmed by obtaining estimated figures consistent with what is described in the literature, and confirming the association between the variables of interest.

Parental practices under the perspective of incarcerated fathers / Práticas parentais na percepção de pais encarcerados / Prácticas parentales en la percepción de los padres encarcelados

This study aimed to evaluate and compare the perception of parenting practices before and during the incarceration of men deprived of liberty. Fifty-seven men aged between 22 and 61 years (M = 36.16; SD = 8.44) participated in the study, with family income of one to two minimum wages (31.6%), did not complete elementary school (54.4%), were married (73.7%), and had two or more children (73.7%) aged 4 to 16 years. They answered socio-demographic questions and the Parenting Practices Inventory (PPI) for conditions in liberty and in prison. Data were analyzed using descriptive analysis, mean comparison tests and Pearson correlation. Regarding their condition of imprisonment, there was a significant reduction in scores of parental practices of "Discipline", "Education" and "Social", but not in "Affection". The scores for "Discipline" for conditions in liberty and in prison showed a strong correlation. The implications of these results are discussed, limitations and future directions are also indicated. (AU)

Este estudo buscou avaliar e comparar a percepção das práticas parentais antes e durante o encarceramento por homens privados de liberdade. Participaram do estudo 57 homens com idades entre 22 e 61 anos (M = 36,16; DP = 8,44), com renda familiar de um a dois salários mínimos (31,6%), ensino fundamental incompleto (54,4%), casados (73,7%) e com dois ou mais filhas/os (78,9%) com idades de 4 a 16 anos. Eles responderam a questões sociodemográficas e ao Inventário de Práticas Parentais (IPP) para as condições em liberdade e em situação de prisão. Realizaram-se análises descritivas, testes de comparação de médias e correlação de Pearson. A situação de prisão representou uma diminuição significativa em práticas parentais de "Disciplina", "Educação" e "Social", mas não em "Afeto". As pontuações em "Disciplina" para as condições em liberdade e em prisão apresentaram forte correlação. São discutidas as implicações desses resultados, bem como apresentadas limitações e direcionamentos futuros. (AU)

El presente estudio buscó evaluar y comparar la percepción de las prácticas parentales antes y durante el encarcelamiento de hombres privados de libertad. Participaron 57 hombres de entre 22 y 61 años (M = 36,16; DS = 8,44), con ingresos familiares de uno o dos salarios mínimos (31,6%), educación primaria incompleta (54,4 %), casados (73,7%) y con dos o más niños (78,9%) con edades entre 4 a 16 años. Los participantes respondieron preguntas sociodemográficas y el Inventario de Prácticas Parentales (IPP) sobre sus condiciones de paternidad en libertad y en prisión. Se realizaron análisis descriptivos, pruebas de comparación de medias y correlación de Pearson. La situación carcelaria representó una disminución significativa en las puntuaciones de las prácticas parentales de "Disciplina", "Educación" y "Social", pero no en "Afectividad". Los escores en el factor "Disciplina" para las condiciones en libertad y en prisión mostraron una fuerte correlación. Se discuten las implicaciones de estos resultados, así como también se presentan las limitaciones y direcciones futuras. (AU)

Estudo-piloto de validação do instrumento Cartoon Test no contexto brasileiro / Pilot study for the validation of the Cartoon Test for the Brazilian context / Estudio piloto de validación del instrumento Cartoon Test en el contexto brasileño

O Cartoon Test é um instrumento que analisa a percepção de crianças e adolescentes acerca do significado de bullying por meio de cenas de interação entre pares no ambiente escolar. Este estudo qualitativo exploratório constitui a segunda etapa de validação do instrumento no Brasil, com os objetivos de verificar se os participantes compreendem as imagens e legendas dos cartoons e que palavras são utilizadas para descrever os comportamentos inadequados. Foram realizados oito grupos focais, com 52 alunos, com idades de oito e 14 anos, de duas cidades do Rio Grande do Sul. Os instrumentos utilizados foram: Questionário sociodemográfico, Folha de registro do pesquisador e Cartoon Test. Realizou-se análise de conteúdo para tratamento dos dados. Os resultados indicaram que o instrumento foi compreendido pelos participantes e o termo bullying foi o mais utilizado para descrever situações agressivas. Para as crianças, sugere-se a redução no número de cartoons, visando evitar a exaustão.(AU)

The Cartoon Test is an instrument that analyzes the perception of children and adolescents about the meaning of bullying through scenes of interaction between peers in the school environment. This qualitative exploratory study is the second phase of validation of the instrument in Brazil. The aim is to verify whether the participants understand both the images and captions of the cartoons and to record the words used to describe the inappropriate behaviors. Eight focus groups were carried out, with 52 students, aged between eight and 14 years, from two cities in Rio Grande do Sul. The instruments used were: sociodemographic questionnaire, record sheet and Cartoon Test. Content analysis was performed. The results showed that the instrument was understood by all the participants and bullying was the word most used to describe the aggressive situations. A reduction in the number of cartoons administered to children is suggested, in order to avoid exhaustion.(AU)

El Cartoon Test es un instrumento que analiza la percepción de niños y adolescentes a respeto del significado de bullying por medio de una escena de interacción entre pares en el ambiente escolar. Este estudio cualitativo exploratorio constituye la segunda etapa de validación del instrumento en Brasil, con el objetivo de verificar que los participantes comprenden las imágenes y leyendas de los cartoons y qué palabras son utilizadas para describir comportamientos inapropiados. Fueron realizados ocho grupos focales, con 52 alumnos, con edades entre ocho y 14 años, de dos ciudades de Rio Grande do Sul. Los instrumentos utilizados fueron: Cuestionario Sociodemográfico, Ficha de Registro del Investigador y Cartoon Test. Se llevo a cabo un análisis de contenido para procesar los datos. Los resultados indicaron que el instrumento fue comprendido por los participantes y el termo bullying fue lo más empleado para describir situaciones agresivas. Para los niños, se sugiere la reducción en el número de cartoons, para evitar el agotamiento.(AU)

Factors associated with condom use behaviour among young university students / Fatores associados ao uso de camisinha entre jovens universitários / Factores asociados con el uso del condom entre jóvenes universitarios

As the rates of sexually transmitted infections among Brazilian youth rise, college students present with low rates of condom use. Understanding which factors affect preventive behaviours may assist in promoting them. This study aimed to test the Theory of Planned Behaviour (TPB) as a model of condom use behaviour among young university students. Data on sexual behaviour, TPB, and personality variables were collected online with 343 sexually active students aged between 18 and 29. Seventy participants also provided follow-up data after 30 days. Structural equation models and ordinal regressions were used to analyse the effects of TPB variables on condom use behaviour. Attitude was the main predictor of behavioural intention in the cross-sectional and longitudinal models. Being in a relationship and lower age at sexual debut were also associated with less frequent condom use behaviour in the cross-sectional analysis. Behavioural intention and perceived control were associated with condom use behaviour. (AU)

Enquanto a incidência de infecções sexualmente transmissíveis cresce entre jovens brasileiros, universitários apresentam pouco uso de preservativos. Compreender quais fatores afetam a adoção de comportamentos preventivos pode auxiliar na sua promoção. Esse estudo testou a Teoria do Comportamento Planejado (TCP) como modelo de uso de camisinha entre jovens universitários. Foram coletados dados sobre comportamento sexual, TCP, e personalidade em questionário online com 343 estudantes sexualmente ativos entre 18 e 29 anos de idade. Setenta participantes também responderam ao follow-up após 30 dias. Modelos de equações estruturais e regressões ordinais foram usados para analisar os efeitos das variáveis da TCP no uso de preservativo. Atitude foi o principal preditor da intenção comportamental nos modelos transversal e longitudinal. Estar em um relacionamento e menor idade na primeira relação sexual também foram associados a uso menos frequente de preservativo na análise transversal. Intenção comportamental e controle percebido foram associados com uso de preservativo. (AU)

Mientras la incidencia de infecciones de transmisión sexual aumenta entre los jóvenes brasileños, los estudiantes universitarios reportan poco uso de preservativos. Comprender qué factores inciden en la adopción de conductas preventivas puede ayudar en su promoción. Este estudio probó la Teoría del Comportamiento Planeado (TCP) como modelo de uso de preservativos entre jóvenes universitarios. Los datos sobre comportamiento sexual, TCP y personalidad fueron recopilados en un cuestionario en línea con 343 estudiantes sexualmente activos entre 18 y 29 años. Setenta participantes también respondieron al seguimiento después de 30 días. Se utilizaron modelos de ecuaciones estructurales y regresiones ordinales para analizar los efectos de las variables de TCP sobre la utilización del condón. La actitud fue el principal predictor de la intención en los modelos transversal y longitudinal. Estar en una relación y una edad más temprana en la primera relación sexual se asociaron con el uso menos frecuente de preservativo en el análisis transversal. La intención conductual y el control percibido se asociaron con el uso de condones. (AU)

Challenges in developmental psychology research during the COVID-19 pandemic / Desafios da pesquisa em psicologia do desenvolvimento durante a pandemia da COVID-19 / Desafíos de la investigación en psicología del desarrollo durante la pandemia de COVID-19

The COVID-19 pandemic brought a series of restructurings necessary for research in Developmental Psychology. The aim of the manuscript is to discuss adaptations we made in our research in this context during the COVID-19 pandemic and to present strategies to adequate research protocols originally designed to occur in person. Although some contexts do not allow the continuity of studies, research at this time can bring essential contributions in this extreme period. This article explores the strategies for adapting recruitment procedures, suggesting dissemination platforms, and using social networks for this purpose. Guidelines are suggested for conducting non-face-to-face interviews with caregivers, ways of assessing the interaction of the mother-child pairs, and problematizing ethical issues. The procedures for returning the results, an ethical researcher commitment, may be improved by resources such as automatic reports. Besides, strategies for better dissemination of the results for the participants are suggested. (AU)

A pandemia COVID-19 trouxe uma série de reestruturações necessárias à pesquisa em Psicologia do Desenvolvimento. O objetivo deste artigo é discutir as adaptações que realizamos em pesquisas neste contexto durante a pandemia de COVID-19 e apresentar estratégias para adequação de protocolos de pesquisa originalmente planejados para ocorrer de forma presencial. Embora alguns contextos não permitam a continuidade dos estudos, pesquisas nesse momento podem trazer importantes contribuições sobre este período ímpar. No presente artigo são exploradas estratégias de adaptação dos procedimentos de recrutamento, sugeridas plataformas de divulgação e como melhor usar as redes sociais para esse fim. Também são descritos procedimentos para realização de entrevistas não presenciais com responsáveis, formas de avaliação da interação das duplas mãe-criança e problematizadas questões éticas. Os procedimentos de devolução dos resultados, um compromisso ético dos pesquisadores, podem ser facilitados por recursos como relatórios automáticos. Além disso, sugerimos estratégias para melhor divulgação dos resultados ao público participante. (AU)

La pandemia del COVID-19 trajo una serie de reestructuraciones necesarias para la investigación en Psicología del Desarrollo. El objetivo de este artículo es discutir las adaptaciones realizadas en las investigaciones en este contexto durante la pandemia de COVID-19 y presentar algunas estrategias para la adaptación de los protocolos de investigación originalmente planeados para ser presenciales. Si bien algunos contextos no permitan la continuidad de los estudios, la investigación en este momento puede aportar importantes avances sobre estos tiempos de crisis. Este artículo explora las estrategias para adaptar los procedimientos de contratación, sugiriendo algunas plataformas de difusión y la mejor manera de utilizar las redes sociales para este fin. También se describen los procedimientos para la realización de entrevistas no presenciales con padres o tutores legales, las formas de evaluar la interacción madre-hijo y las cuestiones éticas. Los procedimientos para la devolución de los resultados, un compromiso ético de los investigadores, pueden verse facilitados por funciones como informes automáticos. Además, se recomienda estrategias para una mejor difusión de los resultados al público participante. (AU)

Cheating Motivation Scale: evidence of validity and reliability / Escala de Motivação para Trapacear: evidências de validade e confiabilidade / Escala de Motivación para Engañar: evidencias de validez y fiabilidad

This study aimed to adapt the Motivation to Cheat Scale (MCS) to the Brazilian student context, gathering evidence of validity based on its internal structure. Two studies were carried out. In Study 1, the 20 items of the MCS were translated into Portuguese and evaluated semantically by ten students, who consider them sufficiently understandable. Subsequently, seeking to know the internal structure of the measure, there was the participation of 212 high school students (M = 16.10 years; SD = 1.02). An exploratory factor analysis indicated the existence of two factors (search for success and moral initiation), which were saturated 18 items. O Study 2 aimed to verify this factorial structure. Logo, the 18 items answered by 229 high school students (M = 16.20 years; SD = 1.23). A confirmatory factorial analysis confirmed bifactorial adjustment. MCS has evidence of validity based on internal structure, which can be used in research outside of Brazil. (AU)

Objetivou-se adaptar a Escala de Motivação para Trapacear (EMT) para o contexto estudantil brasileiro, reunindo evidências de validade baseadas em sua estrutura interna. Realizaram-se dois estudos. No Estudo 1, os 20 itens da EMT foram traduzidos para o português e submetidos à avaliação semântica de dez estudantes, que os consideraram suficientemente compreensíveis. Posteriormente, buscando-se conhecer a estrutura interna da medida, contou-se com a participação de 212 estudantes do Ensino Médio (M = 16,10 anos; DP = 1,02). Uma análise fatorial exploratória indicou a existência de dois fatores (busca de realização e inibição moral), nos quais saturaram 18 itens. O Estudo 2 visou comprovar essa estrutura fatorial. Logo, os 18 itens foram respondidos por 229 estudantes do Ensino Médio (M = 16,20 anos; DP = 1,23). Uma análise fatorial confirmatória comprovou o ajuste bifatorial. A EMT apresentou evidências de validade baseadas na estrutura interna, podendo ser utilizada em pesquisas no Brasil. (AU)

Este estudio tuvo como objetivo adecuar la Escala de Motivación para Engañar (EME) al contexto estudiantil brasileño, recogiendo evidencias de validez a partir de su estructura interna. Se realizaron dos estudios. En el Estudio 1, los 20 ítems de la EME fueron traducidos al portugués y sometidos a la evaluación semántica por parte de diez estudiantes, quienes los consideraron suficientemente comprensibles. Posteriormente, buscando comprender la estructura interna de la medida, participaron 212 estudiantes de la Educación Secundaria (M = 16,10 años; DS = 1,02). Un análisis factorial exploratorio indicó la existencia de dos factores (búsqueda de realización e inhibición moral), en los que se saturaron 18 ítems. El Estudio 2 tuvo como objetivo verificar esta estructura factorial. Por lo que, los 18 ítems fueron respondidos por 229 estudiantes de Secundaria (M = 16,20 años; DS = 1,23). Un análisis factorial confirmatorio demostró la adecuación bifactorial. La EME ha revelado evidencias de validez basadas en la estructura interna, pudiendo ser utilizada en investigaciones brasileñas. (AU)